Marfan syndrome is a genetic disorder that affects the body's connective tissue, which provides support and structure to various tissues and organs. It is caused by changes in the gene that instructs the body to make fibrillin, a protein that helps give connective tissue its strength and flexibility. Marfan syndrome can affect many parts of the body, including the heart, blood vessels, bones, joints, and eyes. People with Marfan syndrome may be tall and thin with disproportionately long arms, legs, fingers, and toes. They may also have chest deformities, scoliosis, and a higher risk of developing heart problems. Treatment typically focuses on managing symptoms and preventing complications through regular monitoring and medical actions such as medications, surgery, or other specialized treatments.

What is "Marfan syndrome"?

Marfan syndrome

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Neurofibromatosis is a genetic disorder that affects the nervous system, causing tumors to form on nerves throughout the body. There are two main types of neurofibromatosis: type 1 (NF1) and type 2 (NF2). NF1 is more common and typically appears in childhood, causing symptoms such as light brown skin patches, skin tumors, and bone deformities. NF2 is less common and usually appears in adolescence or early adulthood, leading to symptoms such as hearing loss, balance problems, and the growth of benign tumors on the nerves responsible for hearing and balance. Treatment for neurofibromatosis focuses on managing symptoms and preventing complications. This may involve regular monitoring, surgery to remove tumors, or other medical actions depending on the individual's symptoms and medical history.

What is "neurofibromatosis"?

neurofibromatosis

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Noonan syndrome is a genetic disorder that affects various parts of the body, causing a wide range of symptoms. It is typically characterized by distinctive facial features, such as widely spaced eyes, low-set ears, and a short neck. Other common features include being shorter than average, heart problems, developmental delays, and bleeding problems. Noonan syndrome can also affect the muscles, bones, and other organs. The seriousness of symptoms can vary widely among affected individuals, even within the same family. Treatment for Noonan syndrome focuses on managing the specific symptoms and complications associated with the condition. This may involve regular medical monitoring, surgery, medications, or other actions adjusted to the individual's needs.

What is "Noonan syndrome"?

Noonan syndrome

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Prader-Willi syndrome is a rare genetic disorder that affects many parts of the body. It is typically characterized by weak muscles, poor growth, and constant feelings of hunger, which can lead to overeating and obesity if not managed carefully. People with Prader-Willi syndrome may also have intellectual disabilities, behavioral problems, and distinctive facial features. The syndrome is caused by abnormalities in a region of chromosome 15, which can result in various physical, cognitive, and behavioral challenges. Treatment for Prader-Willi syndrome focuses on managing symptoms and providing support to address the unique needs of each individual. This may include dietary management, growth hormone therapy, behavioral therapy, and specialized education and support services.

What is "Prader–Willi syndrome"?

Prader–Willi syndrome

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Rett syndrome is a rare genetic disorder that affects brain development, mainly in girls. It is typically characterized by a loss of movement abilities and speech, repetitive hand movements such as twisting or clapping, breathing problems, seizures, and intellectual disability. Rett syndrome is caused by changes in the MECP2 gene, which is important for brain development. The symptoms of Rett syndrome usually become apparent between 6 months and 2 years of age, after a period of normal development. There is currently no cure for Rett syndrome, but treatment focuses on managing symptoms and providing supportive care to improve the individual's quality of life. This may include physical therapy, speech therapy, occupational therapy, and medications to manage symptoms such as seizures or breathing problems.

What is "Rett syndrome"?

Rett syndrome

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Tay-sachs disease is a rare genetic disorder that affects the nervous system. It is typically characterized by a progressive loss of movement abilities, developmental delays, muscle weakness, and an exaggerated startle response. Tay-sachs disease is caused by changes in the HEXA gene, which leads to the buildup of harmful substances in the brain and spinal cord. Symptoms usually appear when a baby or in early childhood and get worse over time, eventually leading to severe disability and early death. There is currently no cure for tay-sachs disease, and treatment focuses on managing symptoms and providing supportive care to improve the individual's quality of life. This may include physical therapy, occupational therapy, and medications to manage symptoms such as seizures or muscle spasms.

What is "tay-sachs disease"?

tay-sachs disease

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Thalassemia is an inherited blood disorder that affects the production of hemoglobin, a protein in red blood cells that carries oxygen throughout the body. It is typically characterized by low levels of hemoglobin and fewer red blood cells than normal, which can lead to anemia and other health problems. Thalassemia can range from mild to severe, depending on the specific genetic changes involved. Symptoms may include fatigue, weakness, pale skin, jaundice, which is the yellowing of the skin and eyes, and bone deformities. Treatment for thalassemia varies depending on the seriousness of the condition but may include blood transfusions, medications to help remove excess iron from the body, and in some cases, bone marrow transplantation.

What is "thalassemia"?

thalassemia

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Tourette syndrome is a neurological disorder characterized by repetitive, involuntary movements and vocalizations known as tics. These tics can range from mild to severe and can include motor tics, such as blinking, shrugging, or jerking movements, and vocal tics, such as grunting, throat clearing, or shouting out words. Tourette syndrome usually begins in childhood and often improves in adulthood, though some individuals may continue to experience symptoms throughout their lives. The exact cause of Tourette syndrome is unknown, but it is believed to involve abnormalities in certain brain regions and neurotransmitters. Treatment for Tourette syndrome typically involves a combination of behavioral therapy, medications to help manage symptoms, and support from healthcare professionals and family members.

What is "Tourette syndrome"?

Tourette syndrome

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Albinism is a genetic condition characterized by a lack of melanin pigment in the skin, hair, and eyes. This results in very pale skin, white or light-colored hair, and light-colored eyes. People with albinism are often sensitive to sunlight and may have vision problems. Albinism is caused by changes in genes involved in the production of melanin. There are different types of albinism, depending on which genes are affected and the extent of pigment loss. While there is no cure for albinism, treatment focuses on managing symptoms and protecting the skin and eyes from sun damage.

What is "albinism"?

albinism

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Angelman syndrome is a rare genetic disorder that affects the nervous system, causing developmental delays, intellectual disability, and movement problems. It is typically characterized by a happy attitude, frequent smiling and laughter, and a strong interest in water. People with Angelman syndrome often have serious difficulties with speech and may communicate using gestures or assistive devices. Other common features include seizures, sleep disturbances, and a unique facial appearance with a wide mouth, widely spaced teeth, and a sticking-out tongue. Angelman syndrome is caused by changes or missing parts in the UBE3A gene on chromosome 15. There is currently no cure for Angelman syndrome, but treatment focuses on managing symptoms and providing supportive care to improve the individual's quality of life. This may include physical therapy, speech therapy, occupational therapy, and medications to manage seizures or behavioral problems.

What is "Angelman syndrome"?

Angelman syndrome

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Apert syndrome is a rare genetic disorder that affects the development of the skull, face, hands, and feet. It is typically characterized by abnormalities such as fused skull bones, a high-arched palate, widely spaced eyes, and fused fingers and toes.. Individuals with Apert syndrome may also have intellectual disability and hearing loss. The condition is caused by changes in the FGFR2 gene, which plays a role in the development of bones and tissues. Treatment for Apert syndrome often involves surgery to correct head, facial, and limb abnormalities, as well as actions to address other medical and developmental issues.

What is "Apert syndrome"?

Apert syndrome

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Charcot-marie-tooth disease (CMT) is a group of inherited neurological disorders that affect the nerves outside the brain and spinal cord, causing muscle weakness and wasting, mainly in the feet and lower legs, but also in the hands in some cases. It is typically characterized by progressive muscle weakness, loss of sensation, and foot deformities. CMT can also cause difficulties with balance and coordination. The condition is caused by changes in genes that affect the structure and function of the nerves outside the brain and spinal cord. Treatment for charcot-marie-tooth disease focuses on managing symptoms and may include physical therapy, orthopedic devices such as braces or orthotic inserts, and in some cases, surgery to correct foot deformities or release compressed nerves.

What is "charcot-marie-tooth disease"?

charcot-marie-tooth disease

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Congenital adrenal hyperplasia (CAH) is a genetic disorder that affects the adrenal glands, which produce hormones that control various bodily functions. In CAH, there is a shortage in one of the enzymes needed to make these hormones, leading to problems in the normal production of cortisol, which is a stress hormone, and aldosterone, which is a hormone that helps control salt and water balance in the body. This can result in a range of symptoms, including abnormal development of sexual characteristics, dehydration, low blood sugar, and salt imbalances. CAH is usually detected through newborn testing or when symptoms appear as a baby or in early childhood. Treatment typically involves lifelong hormone replacement therapy to replace the lacking hormones and manage symptoms.

What is "congenital adrenal hyperplasia"?

congenital adrenal hyperplasia

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Cystic fibrosis is a genetic disorder that affects the lungs and digestive system. It is caused by mutations in the CFTR gene, which leads to the production of thick, sticky mucus that can clog the airways and blocks the pancreas, the organ located behind the stomach that produces enzymes to help digest food and hormones. Symptoms of cystic fibrosis vary but often include persistent coughing, frequent lung infections, difficulty breathing, poor growth, and digestive problems such as difficulty digesting food and absorbing nutrients. Cystic fibrosis is a lifelong condition that requires ongoing medical care. Treatment typically involves medications to thin mucus, prevent infections, improve lung function, and support digestion, as well as therapies and exercise to help clear mucus from the lungs.

What is "cystic fibrosis"?

cystic fibrosis

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Down syndrome, also known as trisomy 21, is a genetic disorder caused by the presence of an extra copy of chromosome 21. It is characterized by a range of physical and intellectual disabilities. Individuals with Down syndrome typically have distinctive facial features, such as almond-shaped eyes, a flat facial profile, and a small nose and mouth. They may also have developmental delays, intellectual disability, and medical conditions such as heart problems, hearing loss, and thyroid problems. While there is no cure for Down syndrome, early support programs and helpful therapies can help individuals with Down syndrome have fulfilling lives.

What is "Down syndrome"?

Down syndrome

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Ehlers Danlos syndrome (EDS) is a group of genetic disorders that affect the body's connective tissues, which provide strength and flexibility to the skin, joints, blood vessels, and other organs. It is characterized by excessive joint flexibility, skin that is easily stretched and bruised, and fragile blood vessels and organs. Individuals with EDS may also experience chronic pain, fatigue, and digestive issues. There are several types of EDS, each with its own set of symptoms and seriousness. Treatment for EDS focuses on managing symptoms and preventing complications through physical therapy, pain management techniques, using supportive devices like braces or wraps, and in some cases, surgery.

What is "Ehlers Danlos syndrome"?

Ehlers Danlos syndrome

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Fabry disease is a rare genetic disorder that results from the buildup of a particular type of fat, called globotriaosylceramide, in the body's cells. This buildup can lead to a range of symptoms, including pain and burning sensations in the hands and feet, clusters of small, dark red spots on the skin, and problems with the kidneys, heart, and nervous system. Fabry disease is caused by changes in the GLA gene, which provides instructions for making an enzyme called alpha-galactosidase A. Without enough of this enzyme, the body cannot break down globotriaosylceramide, leading to its buildup. Treatment for Fabry disease may include enzyme replacement therapy to replace the missing enzyme, medications to manage symptoms such as pain and high blood pressure, and regular monitoring of organ function.

What is "Fabry disease"?

Fabry disease

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Fragile X syndrome is a genetic condition that causes a range of developmental problems, including learning and intellectual disabilities. It is caused by changes in the FMR1 gene, which is responsible for producing a protein important for brain development. Fragile X syndrome is typically characterized by delayed speech and language development, social and behavioral challenges, and certain physical features such as a long face and large ears. In addition to mental and behavioral symptoms, some individuals with fragile X syndrome may also experience sensory sensitivities and medical issues. Treatment for fragile X syndrome focuses on managing symptoms and providing support through educational programs, behavioral therapies, medications, and other supportive services.

What is "fragile X syndrome"?

fragile X syndrome

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Hemophilia is a rare genetic disorder that affects the blood's ability to clot properly. It is typically characterized by prolonged bleeding after injury or surgery, sudden bleeding into joints and muscles, and easy bruising. Hemophilia is caused by changes in genes that produce proteins called clotting factors, which are essential for blood clotting. Treatment for hemophilia usually involves replacing the missing clotting factor through injections of concentrated clotting factor products.

What is "hemophilia"?

hemophilia

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Hemochromatosis is a genetic disorder that causes the body to absorb too much iron from the diet, leading to an excess buildup of iron in various organs and tissues. It is typically characterized by symptoms such as fatigue, joint pain, abdominal pain, and skin discoloration. Over time, untreated hemochromatosis can lead to serious complications such as liver damage, diabetes, heart problems, and arthritis. Treatment for hemochromatosis usually involves regular removal of blood to reduce iron levels in the body.

What is "hemochromatosis"?

hemochromatosis

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Klinefelter syndrome is a genetic condition that occurs in males and is characterized by the presence of an extra X chromosome instead of the usual XY pattern. It is typically associated with physical features such as being tall, having long legs, reduced muscle strength, and small testes, which are the male reproductive organs responsible for producing sperm and testosterone. Individuals with Klinefelter syndrome may also experience developmental delays, learning disabilities, and behavioral issues. Additionally, they may have reduced fertility and an increased risk of conditions such as osteoporosis and breast cancer. Treatment for Klinefelter syndrome may involve hormone therapy to address hormonal imbalances and support physical development.

What is "Klinefelter syndrome"?

Klinefelter syndrome

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Turner syndrome is a genetic condition that affects females and is typically characterized by the absence of all or part of one of the X chromosomes. It is associated with a range of physical features such as being short, having excess skin folds on the side of the neck, low hairline at the back of the neck, and a broad chest with widely spaced nipples. Individuals with Turner syndrome may also experience developmental delays, especially in movement abilities, as well as reproductive issues, such as infertility or early menopause. Additionally, they may have certain medical conditions, including heart problems, kidney problems, and thyroid disorders. Treatment for Turner syndrome may involve growth hormone therapy to increase height, estrogen replacement therapy to start puberty and support bone health, and medical treatments for specific health problems.

What is "turner syndrome"?

turner syndrome

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Williams syndrome is a genetic disorder caused by the loss of genes on chromosome 7. It is characterized by distinctive facial features, such as a broad forehead, short nose with a broad tip, full cheeks, and a wide mouth with full lips. People with Williams syndrome often have a unique personality that includes being highly social, friendly, and having strong language skills but may also experience developmental delays and learning difficulties. Additionally, individuals with Williams syndrome may have heart problems as well as other medical issues like high calcium levels in the blood. Treatment for Williams syndrome involves various types of care, including medical care to address heart and other health issues, educational support to help learning and development, and therapies to improve skills and manage symptoms.

What is "Williams syndrome"?

Williams syndrome

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Huntington's disease is a genetic disorder that causes the progressive breakdown of nerve cells in the brain. It is caused by a change in the HTT gene, which leads to the production of an abnormal form of the huntingtin protein. This abnormal protein gradually damages brain cells, leading to symptoms that typically begin in middle age. Symptoms of Huntington's disease include uncontrolled movements, difficulty with coordination and balance, mental decline, and changes in behavior or personality. As the disease progresses, individuals may have trouble with speaking, swallowing, and performing daily activities. There is currently no cure for Huntington's disease, but treatments are available to help manage symptoms and improve quality of life. These may include medications, physical therapy, and supportive care.

What is "Huntington's disease"?

Huntington's disease

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Sickle-cell disease is a genetic blood disorder that affects the shape and function of red blood cells. Normally, red blood cells are round and flexible, allowing them to move easily through blood vessels. In sickle-cell disease, the red blood cells become stiff and curved like a crescent or sickle. These misshapen cells can block blood flow, leading to pain, infections, and organ damage. Symptoms of sickle-cell disease include episodes of severe pain, fatigue, swelling in the hands and feet, frequent infections, and delayed growth in children. Treatment for sickle-cell disease focuses on managing symptoms and preventing complications and may include medications, blood transfusions, and in some cases, a bone marrow transplant.

What is "sickle-cell disease"?

sickle-cell disease

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Dystrophy refers to a group of genetic disorders characterized by progressive weakness and breakdown of the muscles. These conditions are caused by changes in genes that are important for muscle function and maintenance. Symptoms can vary depending on the type of dystrophy but often include muscle weakness, difficulty walking, frequent falls, and in serious cases, breathing and heart problems. There is currently no cure for dystrophy, but treatment focuses on managing symptoms and improving quality of life through physical therapy, medications, and supportive care.

What is "dystrophy"?

dystrophy

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Von Willebrand disease is a genetic bleeding disorder that affects the blood's ability to clot properly. It is caused by a lack or problem with von Willebrand factor, a protein that helps blood cells stick together and form clots. Individuals with Von Willebrand disease may experience symptoms such as frequent nosebleeds, easy bruising, prolonged bleeding from minor cuts or injuries, and heavy menstrual bleeding in women. The seriousness of Von Willebrand disease varies depending on the level of von Willebrand factor in the blood and how well it functions. Treatment for Von Willebrand disease may involve medications to increase levels of von Willebrand factor or promote clotting, as well as measures to prevent or control bleeding episodes, such as avoiding certain medications or activities that can increase bleeding risk.

What is "Von Willebrand disease"?

von willebrand disease

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Here you will learn some English words related to genetic disorders such as "albinism", "hemophilia", and "dystrophy".

Genetické poruchy

Anglické termíny pro „genetické poruchy“

Genetic Disorders

English Words for "Genetic Disorders"

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